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It was further demonstrated that signaling through the Ras pathway was responsible for this increase ( HIGH GT EXPRESSION AND INTRATUMOR DRUG ACTIVATION The high expression of GT within aggressive and drug-resistant tumors implies that GSH-conjugated prodrugs, activated at the cell surface by GT, should be particularly effective against GT-positive tumors

Pract Diabetes 38:3134 Das A et al (2015) New treatments for diabetic retinopathy

JAK3 Variants in Adults with Myeloid Malignancies and Potential for Response to JAK3 Inhibition

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Other Flavonoids In addition to the previously discussed compounds, several other compounds, each with their own unique properties, have been explored for their therapeutic potential in the management of AD