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Although mitochondrial respiration was noted as unchanged in resting and stimulated CD4+ and CD8+ T cells, CD8+ T cells were found to have a reduction in proton leak, ATP synthesis, and mitochondrial membrane potential (254)
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Developing treatments to enhance GPX3 expression could extend to other diseases characterized by low GPX3 levels
Macegoniuk K, Tabor W, Mazzei L, Cianci M, Giurg M, Olech K, et al
In addition, single nucleotide polymorphisms (SNPs) near the activated leukocyte cell adhesion molecule (ALCAM) gene region are associated with the nonallergic asthma phenotype in adult asthma in GWAS [66]
[DOI] [PMC free article] [PubMed] [Google Scholar] 85
