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Exclusion Criteria Exclusion criteria for drafting the final study were as follows: duplicate publications, irrelevant abstract or research or review reports, articles published before 1990, unauthentic reports lacking the area or localities of the study, data of untargeted disease, non-open access journals, articles that were partially accessed or not indexed or did not provide good citations were removed from the original study

doi: 10.3390/nu12082243

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In the first days after birth, bidirectional communication between the immune system and the microbiota is essential for maintaining microecological balance and immune homeostasis [32,33]

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