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10.1016/j.freeradbiomed.2005.03.014

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[PubMed] [Google Scholar] 27.Freire Jorge P, Wieringa N, de Felice E, van der Horst ICC, Oude Lansink A, Nijsten MW

When the body remains in fight or flight mode for prolonged periods, it: Increases muscle tension throughout the jaw, neck, and head Reduces blood flow to tissues Depletes cellular energy Creates microscopic tissue damage over time, known as microtrauma The result is real pain, real joint sounds, and real functional limitation , even without a distinct injury or disease process

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PKA/AKAP1 and PP2A/Bbeta2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics