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In aggregate, recent human studies find that gut communities rich in these taxa tend to have higher TMAO output

Potential concerns may include: Elevated blood pressure Increased heart rate Sleep disturbances Anxiety symptoms Caffeine dependency Some formulations also use proprietary blends that may not fully disclose ingredient amounts

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A meta-analysis of creatine supplementation in the elderly concluded that creatine enhanced muscle mass, strength, and functional performance during resistance training [54]

Neuropathological hallmarks of the disease include the abnormal deposition of amyloid -peptide (A) fibrils, the main component of senile plaques (SPs), and the intracellular accumulation of neurofibrillary tangles (NFTs), composed of hyperphosphorylated Tau protein (pTau)