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doi: 10.1016/j.ccell.2025.02.006

PD-1 deficiency and PD-1 blockade in tumor model study indicated that mitochondrial functions, including ROS generations, are upregulated in vivo following obliteration of PD-1 signaling [66]

Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice

Hepatocytes exposed to IFN- can lead to the upregulation of MHC class I and the abnormal expression of MHC class II, resulting in further activation of T cells and perpetuation of liver injury [33, 34]

Endogenus glutathione conjugates: occurrence and biological functions