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Proteomics 10:40534076

Notably, astrocyte-specific cholesterol synthesis inhibition significantly alleviates A and Tau pathology in AD mice, indicating glial cholesterol metabolism exerts transcellular regulatory effects (134)

Despite these findings, like the more commonly cited supplements, definitive clinical recommendations cannot be determined without more RCTs of these supplements in the future

Bibcode:2004BiEss..26..778A

One of the best examples is the response to light signals

In particular, the ED 50 of LNPs containing cKK-E12 is as low as 0.002 mg/kg, which is the lowest ED 50 in the liver for all reported LNPs currently