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Nat Commun 12(1):2888, 2021
Immunohistochemical analysis of Iba-1 and GFAP showed that the number of activated astrocytes and microglia increased in both the striatum and substantia nigra after MPTP injection, and treatment with our formulation markedly alleviated MPTP-induced glial cell activation
While primarily based on molecular simulations, these tools aid in understanding the mechanisms of MP/NP interactions with biomolecules and hold potential for future application in neurotoxicity prediction
