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Yes, though it is rare

If youre struggling to lose weight through exercise, or maybe youre feeling sluggish and unmotivated, which led you to give up your diet, you might lack some essential vitamins and minerals that your body needs to lose weight and build muscle effectively

If you're severely lacking in vitamin B12, getting a methylcobalamin injection can help you feel more energized

The weight maintenance after tirzepatide guide addresses the related question of sustaining results during and after the transition off active treatment

Sharma A, et al

If you suspect an adverse reaction to any medicine or supplement, you can report it through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)