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Its considered one of the most important antioxidants in the human body (5)
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The primary function of GR is to catalyze the reduction of oxidized glutathione (GSSG) to its reduced form (GSH) using NADPH as an electron donor

10.1186/s12943-020-01258-7 Summary Keywords ulcerative colitis, GHK-Cu, SIRT1/STAT3 pathway, co-culture system, network pharmacology, molecular docking Citation Mao S, Huang J, Li J, Sun F, Zhang Q, Cheng Q, Zeng W, Lei D, Wang S and Yao J (2025) Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms