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Under-transmission of the variation encoding six alanine residues (ALA6) was observed in the families with autistic disorder, suggesting that this allele may be protective

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CLEC-2 is a transmembrane receptor that upon activation, homodimerizes and initiates Syk-dependent signaling of collagen receptor GPVI, platelet integrin IIb3, promoting platelet aggregation and thrombus formation (142144)
