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Sections were then cooled to room temperature, permeabilized in methanol for 10 min, washed for 10 min three times in PBS and blocked in 10% heat inactivated sheep serum (HISS) in PBS for 2 h

doi:10.1016/j.jad.2013.03.029

Aktualisierte bersicht der Mechanismen

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The 500 mcg per-capsule dose mirrors the per-day intake used in the bulk of rodent oral studies, and the gastric origin of the parent molecule provides a biological rationale for stability through the GI tract a feature documented across multiple oral-administration preclinical models