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TMAO induces ERS via PERK/FoxO1 activation, decreasing insulin receptor expression and causing insulin resistance (81)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Cho YJ, Yun JH, Kim SJ, Kwon HY

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Epidemiological studies showed that genes contribute to the vulnerability of multiple CNS disorders, such as major depressive disorders (MDD), schizophrenia and substance use disorders with heritability respectively of 3142%, 6480%, and 2379% [10,11,12,13]

Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome