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Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study

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Although only IL-1-induced cyclo-oxygenase 2 (COX2) production and IL-8 secretion could be attenuated by the ERK1/2-specific inhibitor PD98059, both TNF- and IL-1 activate ERK and induce the expression of IL-8 and IL-6 [128]

Consistent with this, glutaminolysis-derived -KG promotes M2 activation by increasing fatty acid oxidation and Jmjd3-dependent epigenetic reprogramming of M2-related genes 142

Effects of glutamine supplementation on the immune status in weaning piglets with intrauterine growth retardation