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With continuous advancements in chemical biology, nanotechnology, and synthetic biology, multiple challenges in the clinical translation of natural products are gradually being overcome [301, 302]

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Multidimensional investigation of potential anti-cancer targets of glutamine metabolism and their inhibitors Targeting glutamine metabolism-related enzymes and their inhibitors As indicated by the aforementioned evidence, it can be hypothesised that glutamine-addicted cancer cells are reliant on GLS for survival
Li et al., 2025
