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Although the total collagen content of the disc changes little with disc degeneration, a shift in the proportions of collagen types and in their distributions within the matrix changes, that is, decrease of type II collagen and increase of type I collagen

, Trotter J., Zhang J., et al

38 Role of Hyperhomocysteinemia Mediated By Vitamin B12 Deficiency Vitamin B12 deficiency results in increased homocysteine levels which is shown to be proinflammatory

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Neuregulin 4 suppresses NASH-HCC development by restraining tumor-prone liver microenvironment

doi: 10.1016/j.abb.2010.04.005