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doi: 10.1016/j.neuroscience.2009.07.014

Yes, when administered correctly

Maintaining intestinal barrier integrity is therefore essential to prevent LPS translocation and limit disease progression (57)

It's about correcting the hormonal dysregulation (leptin resistance, ghrelin elevation, insulin resistance) that keeps the body in a fat-storage state despite caloric restriction

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They are also at higher risk of developing pernicious anaemia, a condition where antibodies are produces against the carrier of vitamin B12 in the gut, intrinsic factor