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Clostridial toxins A (TcdA) and B (TcdB) utilise TJ components as receptors, specifically the nectin-3 component of adhesion junctions, which leads to downstream cytoskeletal disruptions and cell death (Roxas and Viswanathan 2018)
Figueiredo HF, Ulrich-Lai YM, Choi DC, Herman JP

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Table 1 Key molecular players in ferroptosis and TAM interactions
