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A 4-week randomized parallel placebo-controlled trial of 0, 25 or 150 mol oral sulfurophane failed to show any changes in alveolar macrophage and bronchial epithelial cell expression of genes encoding antioxidants, or in markers of inflammation in a trial of 89 patients with COPD

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These metabolic pathways interact deeply with core mechanisms such as OS, mitochondrial dysfunction, and abnormal -syn aggregation, collectively forming the complex metabolic background of PD