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Cardiac left ventricular dimensions were obtained under M-mode, and left ventricle ejection fraction (EF) and fractional shortening (FS) were calculated accordingly

Bronchiectasis is an inflammatory disease and is associated with an imbalance between pro- and anti-inflammatory signalling, leading to the recruitment of inflammatory cells and, ultimately, a self-perpetuating cycle of inflammation [23, 27]

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Detection of protein carbonylation Levels of carbonylated proteins were determined with the OxyBlot protein oxidation detection kit following the manufacturers protocol (Millipore, Billerica, MA, USA)

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Pre-weighed tissues were rinsed in PBS and then homogenized in 1 mL cold PBS at pH 6.7 supplemented with 1 mM EDTA, using a Dounce homogenizer on ice