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CrossRef Inhibition of TGF-1/Smad signaling reverses the dedifferentiated phenotype of thyroid cancer cells in three-dimensional culture Li Zhang, Wenjing Gao, Shichen Xu, Hongxun Wu, Yun Zhu, Botao Huang, Xian Cheng, Jing Wu, Huixin Yu, Jiandong Bao, Zichao Zhang Journal of Endocrinological Investigation.2026;[Epub] CrossRef The first experience in Russia of applying a tumor differentiation protocol in a patient with progressive, radioiodine-refractory BRAF-positive papillary thyroid cancer
doi: 10.1007/s00394-019-01931-8 149 MohrAEBasileAJMelisaSCSweazeaKLCarpenterKC
This patient's histology showing uniform round cells with clear cytoplasm rather than pleomorphic cells with hemorrhage and necrosis makes embryonal carcinoma unlikely
Proper reconstitution preserves peptide potency and maintains sterility

Additionally, spray drying techniques using gelatin, gum Arabic, and maltodextrin effectively encapsulated the bioactive components of saffron, preserving its active substances like picaridin and saffron aldehyde, while maintaining the bioactive properties of collagen and further enhancing ACE inhibition [153]

Another study showed that LA (100 mg/kg BW) administration 2 h after OA injection suppressed proliferation in bronchi and the alveolar septum and polynuclear cell infiltration [167]
