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Frontiers in Pharmacology , 12, 654125

doi: 10.3389/fcell.2022.841831 Received 22 December 2021 Accepted 09 February 2022 Published 11 March 2022 Volume 10 - 2022 Edited by Chisa Shukunami, Hiroshima University, Japan Reviewed by Petra Kraus, Clarkson University, United States Danny Chan, The University of Hong Kong, Hong Kong SAR, China Updates Copyright 2022 Hickman, Rathan-Kumar and Peck

(or 0.16 g/mL per-oral) given concurrently with 12.5 mg/kg/day diclofenac in Wistar rats directionally counteracted diclofenac-induced gastric, intestinal, and hepatic lesions and reduced elevations in bilirubin, AST, and ALT though the abstract does not report numeric magnitudes or p-values

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Heres a targeted overview of the stated benefits, typical results, and associated risks to assist in evaluating personal fit for peptide-driven approaches

For 5A1MQ, oral works fine so the case for going sub q is much weaker than it is for actual peptides