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2 Table 2 Clinical Manifestations of Vitamin B12 Deficiency Maternal vitamin B 12 deficiency during pregnancy or while breastfeeding may lead to neural tube defects, developmental delay, failure to thrive, hypotonia, ataxia, and anemia

Just look at this figure at the website of the organization MitoAction: B12 deficiency usually affects like mitochondrial disorders many organ systems, especially the various parts of the nervous system

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.McNeely W, Goa KL

Compounds that disrupt glucose-insulin dynamics typically create hunger patterns that interfere with dietary adherence

NNMT (nicotinamide N-methyltransferase) and NAD+ (nicotinamide adenine dinucleotide) are related but distinct in their individual roles and functions within the body

These factors collectively suggest that the conclusions, while robust, should be interpreted with caution in clinical decision-making