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Head CT conducted using a CT scanner (Aquilion Lightning/Helios i Edition, Canon Medical Systems, Tochigi, Japan) showed occipital bone destruction at the lesion site (Figure 3)

Consistent with previous literature findings of weight loss in rodents following MC4R stimulation [47], mice treated with MT-II demonstrated significant weight loss over the 14-day treatment course

The primary cause of dryness is the lip skin quickly losing moisture through the thin outer layer of skin (a natural process) or through excessive lip licking and lip biting

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