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Martin Caballero I, Hansen J, Leaford D, Pollard S, Hendrich BD (2009)

We hope that by openly sharing this roadmap and materials such as the Investigational New Drug (IND) Template, Roadmap Chart, Conference Guide, among others, we will facilitate other rare disease organizations increase their chances of success (Additional files 1, 2, 3, 4, 5)

Reactive oxygen species induced lipid peroxidation in apoptosis, autophagy, and ferroptosis

doi: 10.1016/j.bcp.2023.115933 121 ZhuoSHeGChenTLiXLiangYWuWet al

As a result, the skin gradually becomes lighter and more radiant

The mechanisms involve enhancing the activity of antioxidant enzymes such as superoxide dismutase (Nemmar et al., 2018), and achieving free radical clearance by regulating the balance of the oxidative/antioxidative system (Rajizadeh et al., 2023)