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Hb not only provides O 2 and increases PDT efficacy, but it also synergizes with SPF, significantly increases the generation of lipid peroxides, downregulates GPX4 expression, and increases tumor cell iron death [196]
doi: 10.1007/s13361-011-0294-6
Mutations in this pathway lead to uncontrolled growth and proliferation
where E is the extinction coefficient of DPPH
