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[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Roussyn I., Briviba K., Masumoto H., Sies H

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H2A-6 conversion to (H2AK119 DHA Ub) probe 100 equiv

[DOI] [PMC free article] [PubMed] [Google Scholar] Detcheverry, F

reported that autoxidation of LA enhanced by Fe(II)/ascorbate under physiological condition (37 C, pH 7.4) generates three main metabolites: a hydroxy-ketone possessing a trans -unsaturation (11( E )-10-OH-13-oxo-OME), a dihydroxy-ketone (11( E )-9,10-DiOH-13-oxo-OME), and an all- trans ketone (9( E ),11( E )-13-oxo-ODE)

This form of tyrosinemia is associated with intellectual impairment, painful corneal eruptions, photophobia, keratitis, and painful palmoplantar hyperkeratosis
