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The mice were randomly grouped and received intravenous injections of DOX (6 mg kg 1 ), Doxil (at a dose equivalent to 6 mg kg 1 DOX), DOX/LAAM GSH-CQDs (at a dose equivalent to 2 and 6 mg kg 1 DOX), saline, and LAAM GSH-CQDs on days 0, 4, 8, and 12

[PMC free article: PMC294537] [PubMed: 8201014] 486

Moriya K, Fujie H, Shintani Y, Yotsuyanagi H, Tsutsumi T, Ishibashi K, et al

doi: 10.1074/jbc.271.30.17739

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The identification of drug-likeness qualities of phyto-components is based on Lipinskis Rule of Five and was checked using the QikProp module of Maestro (QikProp, Maestro Version 12.5.139, Schrdinger, LLC, New York, USA) 80