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methylphenidate) for ADHD all strengthen synaptic dopamine signaling [39], we examined the effects of the TAT-DAT NT on the hyperactivity of SHR rats and we hypothesized that this peptide will reverse such hyperactivity by disrupting the D2R-DAT interaction

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Although there are some differences in the hepatotoxicity caused by alcohol versus that due to excess caloric intake, immunological mechanisms play key roles in the pathogeneses of both ALD and NAFLD

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While all three families can modulate cellular redox status and protein function, they exhibit distinct chemical reactivities, biological targets, and signaling mechanisms that determine immune cell states ( Direct chemical interactions between RSS and ROS/RNS generate novel bioactive species and modulate redox balance

[DOI] [PMC free article] [PubMed] [Google Scholar] 290.Chen F., Yang J., Liu Y., Wang W., Zhu L., Wang W., Yang J., You W