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A randomized, double-blind, placebo-controlled trial in 60 Thai medical students found that glutathione (500 mg/day for 4 weeks) reduced melanin index scores at multiple body sites compared to placebo (Arjinpathana & Asawanonda, J Dermatolog Treat, 2012) [61]

GSSG is the cellular intermediate the cycle returns to GSH through the action of glutathione reductase

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Ovarian ageing: the role of mitochondria in oocytes and follicles

Baudouin-Cornu P et al (2012) Glutathione degradation is a key determinant of glutathione homeostasis