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Acute care hospitals may participate in the BPCI Advanced model in one of two capacities: as a model Participant or as a downstream Episode Initiator

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Also, several pathogenic mechanisms linked to ALS involve redox-sensitive proteins, including protein disulfide isomerase (PDI), thioredoxin, and glutathione (GSH), and recent evidence highlights their importance in neurodegeneration

Drug Targets 20 (9), 15311534

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During a several-month course of NAC treatment, patient#1 had a dramatic improvement in peripheral nerve function