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CHB patients with obesity, diabetes, metabolic syndrome, or cardiovascular disease exhibit markedly higher risks of cirrhosis and HCC, reflecting accelerated inflammation and fibrosis even in the setting of antiviral HBV control (93)

Roofthooft DW, van Beynum IM, de Klerk JC et al , Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen failure

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JAM-A regulates epithelial proliferation through Akt/-catenin signalling

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This is particularly important for medications where consistent absorption is critical for therapeutic effectiveness