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Production of shikonin and its derivatives is influenced by many external factors, as has been previously summarized, 117120 and is in large part modulated by transcriptional regulation of metabolic genes

ROS-mediated activation of protein kinase ERK1/2 causes changes in cell proliferation and survival of endometrial cells, such as those seen in tumor cells [77]

doi: 10.1016/j.bbabio.2009.03.019

doi: 10.3389/fimmu.2022.922702 8 HuppertLAMatthayMAWareLB

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