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Nicolas S, Blasco H, Bigot A, et al

doi: 10.1371/journal.pone.0003815

It could mean the difference between successfully completing a gentle, five-minute movement session and triggering a debilitating, multi-day PEM crash that leaves them bedbound

The final step of BH 4 synthesis actually involves three distinct steps all of which are catalyzed by the NADPH-dependent enzyme, sepiapterin reductase (SR)

All products are made from high-quality premium raw materials and exclusively in certified EU facilities

The IMPRESS trial garnered the strongest level of evidence (two randomized, double-blind, placebo-controlled trials) to support the safety and efficacy of CCH