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International Journal of Environmental Research and Public Health 16 (20): 3811

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Notably, in peripheral blood mononuclear cells (PBMCs) from active CD patients, the upregulated hsa_circRNA_103124 enhances the expression of NLRP3 and GSDMD, key mediators of pyroptosis [82]

Both UK-5099 and -cyano-4-hydroxy cinnamate have been reported to also inhibit the monocarboxylate transporters found at the plasma membrane and therefore potentially cellular pyruvate uptake

[56] In heart failure [edit] In addition to atherosclerosis described above, specific epigenetic changes have been identified in the failing human heart

Vijakumaran U et al