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The mechanistic story is coherent
Persistent metabolic adaptation 6 years after The Biggest Loser competition
doi: 10.1161/01.CIR.96.9.2795 93 LarsenFJSchifferTABorniquelSSahlinKEkblomBLundbergJOet al
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Impairment of complex I leads to increased ROS production and decreased ATP synthesis, contributing to neuronal energy deficits and cell death [161]
