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doi: 10.2337/diabetes.47.10.1578

Moghimipour, E., Gorji, A., Yaghoobi, R., Salimi, A., Latifi, M., Aghakouchakzadeh, M., & Handali, S

You can continue if the overall trend shows improvement even if not yet resolved

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Thus, depending on the make up of the transcription factors bound to the ARE, opposite effects may occur
