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Once a portion of the original H 2 O 2 substrate has been consumed by GPx, any remaining H 2 O 2 reacts with Fe 2+ ions from the FAS via a Fenton-type redox mechanism, oxidizing Fe 2+ to Fe +

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doi: 10.1089/ars.2021.0204

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Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
