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MST1 enhances ROS levels, thereby contributing to the initiation of pyroptosis in pancreatic cancer cells [145]

31 Phenformin has been reported to exhibit anti-thiamine activity in animals, 3234 and as a result, it has been suggested that a possible anti-thiamine effect of metformin might contribute to some cases of metformin-associated lactic acidosis, a rare condition, but one that has been shown to have a mortality rate of 1825%

Besides, plasma SOD level was negatively correlated with MRI severity in patients with CALD (63)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 325.Nigro A., And S., Sisci D