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Washington, DC: The National Academies Press

7 Discussion Current MASLD management primarily relies on lifestyle interventions, including weight reduction, dietary modification, and physical activity ( This review has systematically summarized evidence suggesting that L-carnitine exerts multi-targeted actions against MASLD pathogenesis by promoting lipid metabolism, improving insulin sensitivity, stabilizing hepatocyte function, and inhibiting inflammatory and fibrotic signaling pathways

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Attentively, the findings from animal experiments and organoid studies not only provide crucial insights into the pathogenesis of MASLD but also help guide dietary interventions for improving the condition in patients

doi: 10.1016/j.neuroscience.2010.06.001