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Dopamine D2 and Serotonin 5-HT1A dimeric receptor-binding monomeric antibody scFv as a potential ligand for carrying drugs targeting selected areas of the brain

Although d-penicillamine also shared advantage of oral administration when prescribed at 250 mg given four times for five days of therapy or 40 mg/kg/day for chronic therapy

Among the detected neurons, 57% of the LNvs, 50% of DN1s and 76% of DN2s showed circadian rhythms in 3 69-VNP levels, and 75% of the LNvs showed rhythmic PER-TDT expression

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The participants in this study did not report any serious adverse side effects