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10.1038/nature02789 73 JeongS

Alfthan G, Pekkanen J, Jauhiainen M, Pitkniemi J, Karvonen M, Tuomilehto J, Salonen JT, and Ehnholm C (1994)

As shown in the inset, NAC (40 mm) significantly attenuated the mucosal injury by 5060% with respect to TNBS+ethanol-treated rats in the absence of NAC

This conclusion is corroborated by numerous studies, described above and reviewed elsewhere, 10,103109 that have identified immune activation and inflammation in patients with autism

Most roseoflavin-resistant strains studied until now carry mutations in the regulatory region upstream of the rib operon (more specifically, in the aptamer of the riboswitch), disrupting the negative feedback mechanism, resulting in significantly higher expression 184,185