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BJA Educ

Chronic low-dose cadmium exposure induces liver injury via gut microbiota dysbiosis, even without overt intestinal damage

However, doses above 2030 mg/kg may induce oxidative stress, mitochondrial dysfunction, and inflammatory responses in non-target organs, particularly in the liver and kidney

[PubMed: 19481335] 85
Regulation of the cyclin E gene by transcription factor E2F1

When cells get old or injured, they die, and new cells replace them
