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Myotubes could be induced to hypertrophy by the PI3K/Akt pathway, which increases protein synthesis and blocks the up-regulation of MAFbx and MuRF1 that occurs during muscle atrophy [54, 59]
Notably, concentrations of carnitine have also been documented to be higher in the sperm and seminal plasma of fertile men, compared to men with abnormal semen parameters (Zopfgen et al
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Lopaschuk GD: Current Concepts in Carnitine Research
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This results in an increase of long chain acyl-CoAs, as well as the long chain acylcarnitines
