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The combination of low NADPH concentration and high oxidative stress may lead to the progression and pathogenesis of atherosclerosis [48]

Urban et al., 2012)

TCA cycle and its cofactors The TCA cycle, a core axis of mitochondrial metabolism, relies on Fe-S clusters both directly and indirectly at several different nodes (Fig

The generation of NH 2 -terminal splice variants involves the use of cryptic exons (AR-v1and -v7) or exon skipping (AR-v12) [Figure 8] (156)

It plays a crucial role in lipid metabolism by transporting long-chain fatty acids into the mitochondria, where they are oxidised for energy production