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While it is helpful, it relies on your bodys internal machinery to assemble the final molecule, which can be slow

Yes, long-term use can cause permanent skin thinning, pigmentation, and sensitivity

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Filip N, Cojocaru E, Badulescu OV, Clim A, Pinzariu AC, Bordeianu G, et al

This mechanism suggests BPC-157 functions as a cellular sensitizer to endogenous growth factors rather than as a direct growth factor itself

Perhaps in the future new treatments will come about that solve the issue permanently, but the current treatment options do require at least some maintenance over time to ensure your results continue