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Overall CM, Kleifeld O: Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy

Vitamin D Vitamin D, or cholecalciferol, is a nutrient involved in calcium regulation and phosphate homeostasis, playing a role in immune and musculoskeletal health

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Here, we provide the first evidence of improved healthspan and age-related survival with a therapeutic mAb by demonstrating that treatment with an IGF-1R antagonist in older mice significantly and preferentially improves several indices of healthspan, reduced death from neoplastic disease, and increased mean and median lifespan in females

Unnisa A, Greig NH, Kamal MA