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A study suggested that in GCH1-deficient mice, BH4 could still accumulate with age, which was associated with the production of BH4 by specific gut microbiota, such as intestinal Actinobacteria [118]

The thickness and structural integrity of the ZP are considered important indicators of oocyte quality, particularly in farm animals, and directly influence fertilization success

Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved

However, the protective effect of eat-2 is abrogated by the acs-20 mutation (Fig

Nat Rev Cardiol (2022) 19(9):57792

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