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The role of 8-oxoG repair systems in tumorigenesis and cancer therapy

Although a decrease in circulating and skeletal muscle IGF-1 has been reported in various chronic conditions, including cancer, congestive heart failure, chronic kidney disease, and COPD, and aging [5,163] (Figure 2), more studies are required to determine whether IGF-1 administration could be a therapeutic approach to treat muscle atrophy in these patients (discussed below)

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Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase dependent upon glutathione