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Typical values of GSH in animal cells are in the range 50010,000 M or 0.510 mM [1, 39]

Butt et al., 2016

GPX4 inhibitors and other ferroptosis modulators are currently in clinical trials for various diseases (Table 1), while DHODH inhibitors demonstrating strong preclinical efficacy, represent an emerging frontier for future ferroptosis-based glioblastoma therapy

Pyruvate in reticulocytes is ultimately destined for transport into mitochondria as master fuel for the tricarboxylic acid (TCA) cycle carbon flux

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